Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
HGF
 96.0 45
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
HGF
 63.0 61
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
HGF
 69.0 55
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
HGF
 62.5 52
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
HGF
 49.0 53
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
HGF
 58.0 64
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
HGF
 78.0 65
RA2159 IL-1 alpha 100
ng/mL
 4
HGF
 71.0 53
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
HGF
 69.0 57
N2645 IL-1 alpha 100
ng/mL
 4
HGF
 78.0 45
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
HGF
 65.0 37
RA2708 IL-1 alpha 100
ng/mL
 4
HGF
 59.0 45
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
HGF
 40.5 52
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
HGF
 34.0 58
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
HGF
 39.0 57
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
HGF
 35.0 48
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
HGF
 28.0 44
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
HGF
 34.0 58
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
HGF
 42.0 41
RA2159 TNF-a 100
ng/mL
 4
HGF
 56.5 46
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
HGF
 57.0 41
N2645 TNF-a 100
ng/mL
 4
HGF
 47.0 49
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
HGF
 31.0 45
RA2708 TNF-a 100
ng/mL
 4
HGF
 36.0 45
RA2159 5z-7-oxozeaenol 0.6
uM
 4
HGF
 73.0 37