Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 JNK-IN-8 3.0
uM
 2
IL-4
 18.0 46
RA2708 PH-797804 0.6
uM
 2
IL-4
 17.0 66
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL-4
 19.0 56
RA2159 IKK16 2.0
uM
 2
IL-4
 20.0 65
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-4
 18.0 71
N2645 IKK16 2.0
uM
 2
IL-4
 15.5 58
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-4
 17.0 63
RA2708 IKK16 2.0
uM
 2
IL-4
 20.0 67
RA2159 Tofacitinib 0.3
uM
 2
IL-4
 25.0 77
RA2159 2
IL-4
 20.5 84
N2645 Tofacitinib 0.3
uM
 2
IL-4
 19.0 64
N2645 2
IL-4
 22.0 69
RA2708 Tofacitinib 0.3
uM
 2
IL-4
 19.0 62
RA2708 2
IL-4
 19.0 59
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-4
 87.5 56
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-4
 104.0 72
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-4
 96.0 60
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-4
 94.0 59
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-4
 84.0 65
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-4
 99.0 59
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-4
 123.5 46
RA2159 TNF-a 100
ng/mL
 2
IL-4
 126.0 57
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-4
 95.0 41
N2645 TNF-a 100
ng/mL
 2
IL-4
 101.0 62
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-4
 110.0 58