Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 TNF-a 100
ng/mL
 2
IL-4
 116.0 38
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 20.0 72
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 29.0 75
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 18.0 74
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 27.0 56
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 19.0 67
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 26.0 64
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 79.0 49
RA2159 IL-1 alpha 100
ng/mL
 2
IL-4
 77.0 70
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 43.0 58
N2645 IL-1 alpha 100
ng/mL
 2
IL-4
 60.5 68
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 79.0 63
RA2708 IL-1 alpha 100
ng/mL
 2
IL-4
 76.0 52
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 18.0 65
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 25.0 69
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 18.0 58
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 19.0 57
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 18.0 55
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 17.0 69
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 41.0 87
RA2159 Poly(I:C) 2
ug/mL
 2
IL-4
 51.0 61
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 29.0 45
N2645 Poly(I:C) 2
ug/mL
 2
IL-4
 61.0 70
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 68.0 67
RA2708 Poly(I:C) 2
ug/mL
 2
IL-4
 61.0 59