Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-1B
 41.0 69
RA2708 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-1B
 45.0 87
RA2159 2
IL-1B
 45.0 66
N2645 2
IL-1B
 14.0 95
RA2708 2
IL-1B
 72.0 81
RA2159 JNK-IN-8 3.0
uM
 2
IL-1B
 17.0 89
RA2159 PH-797804 0.6
uM
 2
IL-1B
 30.0 89
N2645 JNK-IN-8 3.0
uM
 2
IL-1B
 14.0 86
N2645 PH-797804 0.6
uM
 2
IL-1B
 13.0 97
RA2708 JNK-IN-8 3.0
uM
 2
IL-1B
 16.0 81
RA2708 PH-797804 0.6
uM
 2
IL-1B
 13.0 75
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL-1B
 17.0 82
RA2159 IKK16 2.0
uM
 2
IL-1B
 15.0 70
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-1B
 13.0 76
N2645 IKK16 2.0
uM
 2
IL-1B
 12.0 72
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-1B
 27.0 81
RA2708 IKK16 2.0
uM
 2
IL-1B
 12.0 90
RA2159 Tofacitinib 0.3
uM
 2
IL-1B
 18.0 89
RA2159 2
IL-1B
 17.0 75
N2645 Tofacitinib 0.3
uM
 2
IL-1B
 16.0 78
N2645 2
IL-1B
 21.0 65
RA2708 Tofacitinib 0.3
uM
 2
IL-1B
 15.0 87
RA2708 2
IL-1B
 16.0 82
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-1B
 439.0 69
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-1B
 452.5 96