Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-1B
 439.0 79
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-1B
 444.0 76
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-1B
 356.5 86
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-1B
 442.0 77
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-1B
 452.0 70
RA2159 TNF-a 100
ng/mL
 2
IL-1B
 441.5 58
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-1B
 474.0 65
N2645 TNF-a 100
ng/mL
 2
IL-1B
 392.0 77
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-1B
 479.5 82
RA2708 TNF-a 100
ng/mL
 2
IL-1B
 462.0 64
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 27.0 83
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 22.0 87
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 15.5 80
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 22.0 72
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 61.0 82
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 22.0 74
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 90.0 82
RA2159 IL-1 alpha 100
ng/mL
 2
IL-1B
 81.5 84
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 45.0 73
N2645 IL-1 alpha 100
ng/mL
 2
IL-1B
 57.0 73
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 91.5 78
RA2708 IL-1 alpha 100
ng/mL
 2
IL-1B
 93.0 51
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-1B
 23.0 79
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-1B
 22.0 81
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-1B
 17.0 82