Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 JNK-IN-8 3.0
uM
 3
TNFb
 29.0 38
RA1869 PH-797804 0.6
uM
 3
TNFb
 34.0 30
N2759 JNK-IN-8 3.0
uM
 3
TNFb
 29.0 46
N2759 PH-797804 0.6
uM
 3
TNFb
 33.0 41
RA1931 JNK-IN-8 3.0
uM
 3
TNFb
 34.0 33
RA1931 PH-797804 0.6
uM
 3
TNFb
 29.0 24
N2586 JNK-IN-8 3.0
uM
 3
TNFb
 26.0 29
N2586 PH-797804 0.6
uM
 3
TNFb
 28.5 34
0
TNFb
 39.0 45
0
TNFb
 37.0 29
0
TNFb
 37.5 36
RA2159 5z-7-oxozeaenol 0.6
uM
 4
TNFb
 35.5 64
RA2159 IKK16 2.0
uM
 4
TNFb
 33.0 43
N2645 5z-7-oxozeaenol 0.6
uM
 4
TNFb
 32.0 61
N2645 IKK16 2.0
uM
 4
TNFb
 29.0 59
RA2708 5z-7-oxozeaenol 0.6
uM
 4
TNFb
 30.0 57
RA2708 IKK16 2.0
uM
 4
TNFb
 34.0 69
RA2159 Tofacitinib 0.3
uM
 4
TNFb
 35.0 60
RA2159 4
TNFb
 34.0 59
N2645 Tofacitinib 0.3
uM
 4
TNFb
 27.5 44
N2645 4
TNFb
 33.0 43
RA2708 Tofacitinib 0.3
uM
 4
TNFb
 34.0 41
RA2708 4
TNFb
 30.0 37
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 30.0 49
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 29.0 67