Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 30.5 56
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 28.0 61
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 27.0 47
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 29.0 43
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 32.0 59
RA2159 Poly(I:C) 2
ug/mL
 4
TNFb
 27.0 62
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 36.0 63
N2645 Poly(I:C) 2
ug/mL
 4
TNFb
 27.0 57
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 30.0 54
RA2708 Poly(I:C) 2
ug/mL
 4
TNFb
 32.5 60
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 85.5 66
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 90.0 53
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 87.0 71
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 83.0 42
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 82.0 62
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 78.0 55
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 84.5 70
RA2159 IL-1 alpha 100
ng/mL
 4
TNFb
 71.0 49
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 72.5 50
N2645 IL-1 alpha 100
ng/mL
 4
TNFb
 85.0 50
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 82.5 48
RA2708 IL-1 alpha 100
ng/mL
 4
TNFb
 72.0 47
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
TNFb
 33.0 41
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
TNFb
 33.0 53
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
TNFb
 29.0 82