Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 PH-797804 0.6
uM
 3
IL-17
 30.0 48
N2586 JNK-IN-8 3.0
uM
 3
IL-17
 33.0 45
N2586 PH-797804 0.6
uM
 3
IL-17
 31.0 43
0
IL-17
 46.0 24
0
IL-17
 49.5 16
0
IL-17
 51.5 14
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL-17
 38.0 25
RA2159 IKK16 2.0
uM
 4
IL-17
 43.0 47
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL-17
 42.0 44
N2645 IKK16 2.0
uM
 4
IL-17
 44.0 42
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL-17
 44.0 34
RA2708 IKK16 2.0
uM
 4
IL-17
 46.5 26
RA2159 Tofacitinib 0.3
uM
 4
IL-17
 42.5 38
RA2159 4
IL-17
 49.0 25
N2645 Tofacitinib 0.3
uM
 4
IL-17
 40.5 26
N2645 4
IL-17
 38.5 24
RA2708 Tofacitinib 0.3
uM
 4
IL-17
 34.0 24
RA2708 4
IL-17
 30.0 29
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 49.0 38
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 56.0 39
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 41.0 37
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 43.0 37
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 45.5 34
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 46.5 32
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 64.0 28