Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Poly(I:C) 2
ug/mL
 4
IL-17
 90.0 23
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 51.0 23
N2645 Poly(I:C) 2
ug/mL
 4
IL-17
 56.5 26
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 80.0 20
RA2708 Poly(I:C) 2
ug/mL
 4
IL-17
 93.0 15
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 44.0 30
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 47.0 31
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 33.0 25
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 50.0 51
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 44.0 29
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 59.0 29
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 85.0 41
RA2159 IL-1 alpha 100
ng/mL
 4
IL-17
 94.0 21
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 72.0 23
N2645 IL-1 alpha 100
ng/mL
 4
IL-17
 71.0 26
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 87.0 24
RA2708 IL-1 alpha 100
ng/mL
 4
IL-17
 87.0 35
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-17
 93.5 34
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-17
 90.0 31
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-17
 46.0 37
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-17
 76.0 33
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-17
 88.0 36
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-17
 63.0 31
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-17
 104.0 23
RA2159 TNF-a 100
ng/mL
 4
IL-17
 122.0 37