Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 TNF-a 100
ng/mL
 1
IL-10
 63.0 71
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-10
 82.5 64
RA1931 TNF-a 100
ng/mL
 1
IL-10
 87.0 57
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-10
 64.0 71
N2586 TNF-a 100
ng/mL
 1
IL-10
 61.0 57
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 44.0 57
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 42.5 50
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 46.0 40
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 40.0 48
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 48.0 71
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 57.0 49
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 47.0 43
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 48.0 61
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 59.0 60
RA1869 IL-1 alpha 100
ng/mL
 1
IL-10
 74.5 50
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 54.0 59
N2759 IL-1 alpha 100
ng/mL
 1
IL-10
 71.0 63
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 73.5 56
RA1931 IL-1 alpha 100
ng/mL
 1
IL-10
 62.0 64
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 63.5 44
N2586 IL-1 alpha 100
ng/mL
 1
IL-10
 67.0 52
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 44.0 56
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 50.0 53
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 45.0 51
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 33.0 47