Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 5z-7-oxozeaenol 0.6
uM
 1
IL-10
 44.0 67
N2759 IKK16 2.0
uM
 1
IL-10
 43.5 56
RA1931 5z-7-oxozeaenol 0.6
uM
 1
IL-10
 51.0 86
RA1931 IKK16 2.0
uM
 1
IL-10
 49.0 65
N2586 5z-7-oxozeaenol 0.6
uM
 1
IL-10
 39.5 60
N2586 IKK16 2.0
uM
 1
IL-10
 47.0 45
RA1869 Tofacitinib 0.3
uM
 1
IL-10
 51.5 62
RA1869 1
IL-10
 49.0 69
N2759 Tofacitinib 0.3
uM
 1
IL-10
 47.0 60
N2759 1
IL-10
 47.0 72
RA1931 Tofacitinib 0.3
uM
 1
IL-10
 60.5 60
RA1931 1
IL-10
 44.0 61
N2586 Tofacitinib 0.3
uM
 1
IL-10
 45.0 74
N2586 1
IL-10
 37.0 38
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-10
 55.0 49
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-10
 56.0 69
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-10
 56.0 61
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-10
 57.5 82
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-10
 61.0 70
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-10
 60.5 64
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-10
 56.0 64
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-10
 53.0 56
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-10
 75.5 62
RA1869 TNF-a 100
ng/mL
 1
IL-10
 75.0 55
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-10
 49.0 66