Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 39.0 61
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 43.0 59
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 34.0 37
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 40.0 61
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 55.5 54
RA1869 Poly(I:C) 2
ug/mL
 1
IL-10
 51.5 46
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 52.0 62
N2759 Poly(I:C) 2
ug/mL
 1
IL-10
 49.0 68
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 54.0 61
RA1931 Poly(I:C) 2
ug/mL
 1
IL-10
 63.0 53
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 60.0 55
N2586 Poly(I:C) 2
ug/mL
 1
IL-10
 55.0 50
RA1869 5z-7-oxozeaenol 0.6
uM
 1
IL-10
 39.0 56
RA1869 IKK16 2.0
uM
 1
IL-10
 45.0 47
N2759 5z-7-oxozeaenol 0.6
uM
 1
IL-10
 42.5 68
N2759 IKK16 2.0
uM
 1
IL-10
 42.0 58
RA1931 5z-7-oxozeaenol 0.6
uM
 1
IL-10
 38.5 86
RA1931 IKK16 2.0
uM
 1
IL-10
 46.0 64
N2586 5z-7-oxozeaenol 0.6
uM
 1
IL-10
 40.0 67
N2586 IKK16 2.0
uM
 1
IL-10
 43.0 49
RA1869 Tofacitinib 0.3
uM
 1
IL-10
 47.5 60
RA1869 1
IL-10
 51.0 75
N2759 Tofacitinib 0.3
uM
 1
IL-10
 38.0 54
N2759 1
IL-10
 40.0 47
RA1931 Tofacitinib 0.3
uM
 1
IL-10
 56.0 57