Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 Tofacitinib 0.3
uM
 4
IL-6
 1163.0 41
N2645 4
IL-6
 1465.0 33
RA2708 Tofacitinib 0.3
uM
 4
IL-6
 1028.5 28
RA2708 4
IL-6
 2595.0 26
RA2159 4
IL-6
 4648.5 32
N2645 4
IL-6
 1342.0 37
RA2708 4
IL-6
 1664.0 31
RA2159 JNK-IN-8 3.0
uM
 4
IL-6
 3377.0 27
RA2159 PH-797804 0.6
uM
 4
IL-6
 6115.5 30
N2645 JNK-IN-8 3.0
uM
 4
IL-6
 824.0 43
N2645 PH-797804 0.6
uM
 4
IL-6
 1037.5 24
RA2708 JNK-IN-8 3.0
uM
 4
IL-6
 1626.0 31
RA2708 PH-797804 0.6
uM
 4
IL-6
 2044.0 40
RA2159 Poly(I:C) 2
ug/mL
 4
IL-6
 30351.0 29
N2645 Poly(I:C) 2
ug/mL
 4
IL-6
 7736.0 41
RA2708 Poly(I:C) 2
ug/mL
 4
IL-6
 34332.5 36
RA2159 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-6
 17115.0 43
RA2159 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-6
 22317.5 20
N2645 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-6
 4654.0 34
N2645 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-6
 11652.0 26
RA2708 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-6
 28981.0 37
RA2708 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-6
 24988.0 31
RA2159 IL-1 alpha 100
ng/mL
 4
IL-6
 38589.0 43
N2645 IL-1 alpha 100
ng/mL
 4
IL-6
 26197.0 43
RA2708 IL-1 alpha 100
ng/mL
 4
IL-6
 38611.0 35