Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IL-1 alpha 100
ng/mL
 4
IL-6
 36626.0 30
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-6
 23151.0 38
N2645 IL-1 alpha 100
ng/mL
 4
IL-6
 28753.0 30
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-6
 39068.0 35
RA2708 IL-1 alpha 100
ng/mL
 4
IL-6
 40254.0 33
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-6
 7556.0 34
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-6
 16567.0 35
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-6
 603.0 39
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-6
 3046.0 34
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-6
 1979.0 54
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-6
 7298.0 42
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-6
 19169.0 50
RA2159 TNF-a 100
ng/mL
 4
IL-6
 24280.0 35
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-6
 9851.5 48
N2645 TNF-a 100
ng/mL
 4
IL-6
 11941.5 32
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-6
 10687.0 37
RA2708 TNF-a 100
ng/mL
 4
IL-6
 13615.5 28
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL-6
 3799.5 40
RA2159 IKK16 2.0
uM
 4
IL-6
 5630.0 46
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL-6
 834.0 41
N2645 IKK16 2.0
uM
 4
IL-6
 754.0 33
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL-6
 1587.0 34
RA2708 IKK16 2.0
uM
 4
IL-6
 2462.5 44
RA2159 Tofacitinib 0.3
uM
 4
IL-6
 3894.0 18
RA2159 4
IL-6
 6943.0 30