Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 2
IL-6
 1682.0 66
RA2159 JNK-IN-8 3.0
uM
 2
IL-6
 1975.0 64
RA2159 PH-797804 0.6
uM
 2
IL-6
 2409.5 70
N2645 JNK-IN-8 3.0
uM
 2
IL-6
 857.5 80
N2645 PH-797804 0.6
uM
 2
IL-6
 836.5 60
RA2708 JNK-IN-8 3.0
uM
 2
IL-6
 1110.0 55
RA2708 PH-797804 0.6
uM
 2
IL-6
 1196.0 57
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL-6
 2085.0 77
RA2159 IKK16 2.0
uM
 2
IL-6
 2330.5 80
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-6
 827.0 71
N2645 IKK16 2.0
uM
 2
IL-6
 636.0 92
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-6
 1310.0 79
RA2708 IKK16 2.0
uM
 2
IL-6
 1368.0 101
RA2159 Tofacitinib 0.3
uM
 2
IL-6
 2157.0 59
RA2159 2
IL-6
 3070.0 82
N2645 Tofacitinib 0.3
uM
 2
IL-6
 932.0 73
N2645 2
IL-6
 836.0 64
RA2708 Tofacitinib 0.3
uM
 2
IL-6
 1282.5 84
RA2708 2
IL-6
 1331.0 67
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-6
 4076.0 73
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-6
 11196.0 41
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-6
 1433.5 72
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-6
 2118.0 63
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-6
 1679.0 59
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-6
 3573.5 62