Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2708 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | IL-8 | 12628.0 | 27 | |
| RA2708 | PH-797804 | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | IL-8 | 12395.0 | 17 | |
| RA2159 | TNF-a | 100 | ng/mL | 4 | IL-8 | 11809.5 | 16 | ||||
| N2645 | TNF-a | 100 | ng/mL | 4 | IL-8 | 11453.0 | 23 | ||||
| RA2708 | TNF-a | 100 | ng/mL | 4 | IL-8 | 11113.0 | 24 | ||||
| RA2159 | JNK-IN-8 | 3.0 | uM | TNF-a | 100 | ng/mL | 4 | IL-8 | 10255.0 | 29 | |
| RA2159 | PH-797804 | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | IL-8 | 9831.0 | 25 | |
| N2645 | JNK-IN-8 | 3.0 | uM | TNF-a | 100 | ng/mL | 4 | IL-8 | 10193.0 | 23 | |
| N2645 | PH-797804 | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | IL-8 | 10026.0 | 23 | |
| RA2708 | JNK-IN-8 | 3.0 | uM | TNF-a | 100 | ng/mL | 4 | IL-8 | 9037.0 | 22 | |
| RA2708 | PH-797804 | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | IL-8 | 10119.0 | 19 | |
| 0 | IL-8 | 14.0 | 19 | ||||||||
| 0 | IL-8 | 16.0 | 37 | ||||||||
| 0 | IL-8 | 17.0 | 41 | ||||||||
| RA2159 | 4 | IL-8 | 81.5 | 18 | |||||||
| N2645 | 4 | IL-8 | 111.5 | 34 | |||||||
| RA2708 | 4 | IL-8 | 582.0 | 19 | |||||||
| RA2159 | JNK-IN-8 | 3.0 | uM | 4 | IL-8 | 71.0 | 25 | ||||
| RA2159 | PH-797804 | 0.6 | uM | 4 | IL-8 | 183.0 | 20 | ||||
| N2645 | JNK-IN-8 | 3.0 | uM | 4 | IL-8 | 87.0 | 21 | ||||
| N2645 | PH-797804 | 0.6 | uM | 4 | IL-8 | 92.0 | 25 | ||||
| RA2708 | JNK-IN-8 | 3.0 | uM | 4 | IL-8 | 328.0 | 24 | ||||
| RA2708 | PH-797804 | 0.6 | uM | 4 | IL-8 | 479.0 | 31 | ||||
| TNF-a | 100 | ng/mL | 0 | IL-8 | 71.0 | 41 | |||||
| IL-1 alpha | 100 | ng/mL | 0 | IL-8 | 14.0 | 67 |