Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 IL-1 alpha 100
ng/mL
 3
IL-7
 23.0 51
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 23.0 71
N2759 IL-1 alpha 100
ng/mL
 3
IL-7
 23.0 53
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 23.0 59
RA1931 IL-1 alpha 100
ng/mL
 3
IL-7
 27.0 45
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 18.0 76
N2586 IL-1 alpha 100
ng/mL
 3
IL-7
 20.0 58
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-7
 14.0 33
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-7
 18.0 43
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-7
 15.5 62
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-7
 19.0 81
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-7
 21.0 81
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-7
 14.5 40
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-7
 15.0 64
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-7
 16.5 76
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-7
 23.0 55
RA1869 TNF-a 100
ng/mL
 3
IL-7
 27.5 38
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-7
 21.5 70
N2759 TNF-a 100
ng/mL
 3
IL-7
 21.5 60
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-7
 25.0 72
RA1931 TNF-a 100
ng/mL
 3
IL-7
 24.5 50
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-7
 19.0 47
N2586 TNF-a 100
ng/mL
 3
IL-7
 20.0 52
RA1869 5z-7-oxozeaenol 0.6
uM
 3
IL-7
 11.0 47
RA1869 IKK16 2.0
uM
 3
IL-7
 16.0 46