Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 14.0 70
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 14.5 76
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 25.0 62
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 21.0 71
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 31.0 55
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 23.0 55
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 14.0 74
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 15.0 73
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 24.0 71
RA1869 Poly(I:C) 2
ug/mL
 3
IL-7
 20.0 73
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 23.0 77
N2759 Poly(I:C) 2
ug/mL
 3
IL-7
 23.0 63
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 22.0 61
RA1931 Poly(I:C) 2
ug/mL
 3
IL-7
 27.5 68
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 18.0 70
N2586 Poly(I:C) 2
ug/mL
 3
IL-7
 18.0 59
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 11.0 51
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 16.0 60
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 19.0 52
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 20.5 68
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 19.0 49
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 23.0 53
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 15.0 81
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 17.0 66
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 20.0 59