Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 JNK-IN-8 3.0
uM
 2
IL-4
 19.0 55
RA2708 PH-797804 0.6
uM
 2
IL-4
 21.0 60
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL-4
 20.0 66
RA2159 IKK16 2.0
uM
 2
IL-4
 21.0 61
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-4
 21.0 56
N2645 IKK16 2.0
uM
 2
IL-4
 21.0 67
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-4
 26.0 55
RA2708 IKK16 2.0
uM
 2
IL-4
 19.5 66
RA2159 Tofacitinib 0.3
uM
 2
IL-4
 20.0 62
RA2159 2
IL-4
 23.0 60
N2645 Tofacitinib 0.3
uM
 2
IL-4
 22.0 69
N2645 2
IL-4
 22.0 81
RA2708 Tofacitinib 0.3
uM
 2
IL-4
 20.0 67
RA2708 2
IL-4
 20.0 74
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-4
 66.0 47
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-4
 85.0 44
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-4
 60.0 51
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-4
 67.0 63
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-4
 63.0 58
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-4
 67.0 48
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-4
 94.0 59
RA2159 TNF-a 100
ng/mL
 2
IL-4
 89.0 43
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-4
 63.0 54
N2645 TNF-a 100
ng/mL
 2
IL-4
 74.0 45
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-4
 83.0 48