Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 TNF-a 100
ng/mL
 2
IL-4
 70.5 38
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 19.0 50
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 23.5 54
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 20.5 76
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 25.0 57
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 18.0 53
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 27.5 50
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 64.0 56
RA2159 IL-1 alpha 100
ng/mL
 2
IL-4
 72.0 61
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 38.0 42
N2645 IL-1 alpha 100
ng/mL
 2
IL-4
 38.0 51
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 66.5 40
RA2708 IL-1 alpha 100
ng/mL
 2
IL-4
 62.0 48
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 21.5 78
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 26.0 59
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 20.0 60
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 23.0 54
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 22.0 58
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 24.0 59
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 38.5 66
RA2159 Poly(I:C) 2
ug/mL
 2
IL-4
 54.0 63
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 26.0 46
N2645 Poly(I:C) 2
ug/mL
 2
IL-4
 29.0 59
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-4
 56.0 47
RA2708 Poly(I:C) 2
ug/mL
 2
IL-4
 54.0 54