Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2708 | JNK-IN-8 | 3.0 | uM | TNF-a | 100 | ng/mL | 4 | MMP-1 | 46888.0 | 52 | |
| RA2708 | IL-1 alpha | 100 | ng/mL | 4 | MMP-1 | 43498.0 | 44 | ||||
| RA2708 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 2 | MMP-1 | 43350.5 | 52 | |
| RA2708 | JNK-IN-8 | 3.0 | uM | TNF-a | 100 | ng/mL | 2 | MMP-1 | 43111.0 | 53 | |
| RA2708 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | MMP-1 | 42679.0 | 66 | |
| RA2708 | IL-1 alpha | 100 | ng/mL | 4 | IL-6 | 40254.0 | 33 | ||||
| RA2708 | IL-1 alpha | 100 | ng/mL | 4 | MMP-3 | 39153.0 | 47 | ||||
| RA2708 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 4 | IL-6 | 39068.0 | 35 | |
| RA2708 | TNF-a | 100 | ng/mL | 4 | MMP-1 | 39016.5 | 64 | ||||
| RA2708 | TNF-a | 100 | ng/mL | 4 | MMP-1 | 38971.0 | 43 | ||||
| RA2708 | IL-1 alpha | 100 | ng/mL | 4 | IL-6 | 38611.0 | 35 | ||||
| RA2159 | IL-1 alpha | 100 | ng/mL | 4 | IL-6 | 38589.0 | 43 | ||||
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 36633.0 | 51 | |
| RA2159 | IL-1 alpha | 100 | ng/mL | 4 | IL-6 | 36626.0 | 30 | ||||
| RA2708 | IL-1 alpha | 100 | ng/mL | 2 | MMP-1 | 36593.5 | 60 | ||||
| RA2159 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | IL-6 | 36580.0 | 41 | |
| RA2708 | Poly(I:C) | 2 | ug/mL | 4 | IL-6 | 36535.0 | 33 | ||||
| RA2708 | TNF-a | 100 | ng/mL | 2 | MMP-1 | 36355.0 | 77 | ||||
| RA2159 | IL-1 alpha | 100 | ng/mL | 2 | IL-6 | 36270.0 | 66 | ||||
| RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 4 | IL-6 | 36090.0 | 44 | |
| RA2708 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 2 | IL-6 | 36019.0 | 51 | |
| N2759 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 35892.0 | 50 | |
| RA2708 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 2 | IL-6 | 35882.0 | 67 | |
| RA2708 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 2 | MMP-1 | 35785.5 | 52 | |
| RA1931 | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 35766.0 | 61 |