Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 4
IL18
 6
RA1931 JNK-IN-8 3.0
uM
 3
MMP-2
 327.0 7
RA1931 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 3
MMP-2
 352.0 7
RA2159 4
LIF
 48.5 8
RA1869 JNK-IN-8 3.0
uM
 3
MMP-2
 447.5 8
0
MCP-1 (MCAF)
 12.0 9
TNF-a 100
ng/mL
 0
IL-9
 46.0 9
TNF-a 100
ng/mL
 0
MMP-1
 16.0 9
TNF-a 100
ng/mL
 0
MMP-2
 16.0 9
0
MCP-1 (MCAF)
 22.0 9
N2586 TNF-a 100
ng/mL
 1
MMP-2
 322.0 9
0
IL-12 (p70)
 13.0 10
RA1931 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 3
MMP-1
 17137.0 10
RA2159 4
MIF
 47.5 10
RA1931 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 3
MMP-3
 1014.5 10
0
MMP-2
 1.0 11
N2586 TNF-a 100
ng/mL
 1
MMP-3
 2741.0 11
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 426.0 11
N2586 PH-797804 0.6
uM
 TNF-a 100
ng/mL
 3
MMP-3
 1227.0 11
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MMP-3
 590.0 11
N2586 PH-797804 0.6
uM
 TNF-a 100
ng/mL
 3
MMP-2
 302.0 11
RA1931 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 1145.0 11
Poly(I:C) 2
ug/mL
 0
MCP-1 (MCAF)
 22.0 11
0
TNFb
 44.0 11
N2645 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 4
IP-10
 7694.0 12
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