Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 JNK-IN-8 3.0
uM
 2
M-CSF
 291.5 34
N2645 PH-797804 0.6
uM
 2
M-CSF
 249.0 39
RA2708 JNK-IN-8 3.0
uM
 2
M-CSF
 289.0 37
RA2708 PH-797804 0.6
uM
 2
M-CSF
 255.5 42
RA2159 5z-7-oxozeaenol 0.6
uM
 2
M-CSF
 208.0 47
RA2159 IKK16 2.0
uM
 2
M-CSF
 209.0 50
N2645 5z-7-oxozeaenol 0.6
uM
 2
M-CSF
 222.0 31
N2645 IKK16 2.0
uM
 2
M-CSF
 203.5 38
RA2708 5z-7-oxozeaenol 0.6
uM
 2
M-CSF
 238.5 40
RA2708 IKK16 2.0
uM
 2
M-CSF
 253.0 49
RA2159 Tofacitinib 0.3
uM
 2
M-CSF
 258.0 35
RA2159 2
M-CSF
 297.0 53
N2645 Tofacitinib 0.3
uM
 2
M-CSF
 249.0 35
N2645 2
M-CSF
 214.0 41
RA2708 Tofacitinib 0.3
uM
 2
M-CSF
 277.0 37
RA2708 2
M-CSF
 284.0 39
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
M-CSF
 344.0 44
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
M-CSF
 335.0 53
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
M-CSF
 290.0 45
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
M-CSF
 319.0 37
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
M-CSF
 356.0 39
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
M-CSF
 288.5 32
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
M-CSF
 564.5 30
RA2159 TNF-a 100
ng/mL
 2
M-CSF
 569.0 45
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
M-CSF
 429.0 39