Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 TNF-a 100
ng/mL
 2
M-CSF
 413.0 51
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
M-CSF
 603.0 30
RA2708 TNF-a 100
ng/mL
 2
M-CSF
 551.0 29
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 289.0 43
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 258.0 47
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 301.0 44
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 282.0 39
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 294.5 34
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 314.5 26
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 470.0 41
RA2159 IL-1 alpha 100
ng/mL
 2
M-CSF
 475.0 43
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 508.0 37
N2645 IL-1 alpha 100
ng/mL
 2
M-CSF
 508.5 50
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 491.5 40
RA2708 IL-1 alpha 100
ng/mL
 2
M-CSF
 383.0 34
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 267.0 55
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 276.5 28
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 197.5 48
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 207.0 41
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 158.0 29
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 173.0 39
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 313.0 52
RA2159 Poly(I:C) 2
ug/mL
 2
M-CSF
 368.5 38
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 183.0 43
N2645 Poly(I:C) 2
ug/mL
 2
M-CSF
 239.0 39