Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL18
 28.5 64
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL18
 28.5 70
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL18
 32.0 76
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL18
 29.0 64
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL18
 30.0 57
RA2159 TNF-a 100
ng/mL
 4
IL18
 34.5 48
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL18
 33.0 60
N2645 TNF-a 100
ng/mL
 4
IL18
 30.5 60
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL18
 30.5 52
RA2708 TNF-a 100
ng/mL
 4
IL18
 27.0 39
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL18
 40.0 47
RA2159 IKK16 2.0
uM
 4
IL18
 33.5 46
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL18
 33.0 41
N2645 IKK16 2.0
uM
 4
IL18
 31.0 55
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL18
 30.0 43
RA2708 IKK16 2.0
uM
 4
IL18
 28.0 59
RA2159 Tofacitinib 0.3
uM
 4
IL18
 34.0 45
RA2159 4
IL18
 31.0 45
N2645 Tofacitinib 0.3
uM
 4
IL18
 29.0 49
N2645 4
IL18
 30.5 52
RA2708 Tofacitinib 0.3
uM
 4
IL18
 29.0 35
RA2708 4
IL18
 25.5 48
RA2159 4
IL18
 6
N2645 4
IL18
 29.0 49
RA2708 4
IL18
 30.0 60