Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL18
 24.0 49
RA2159 IKK16 2.0
uM
 2
IL18
 21.5 56
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL18
 20.0 45
N2645 IKK16 2.0
uM
 2
IL18
 20.0 54
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL18
 17.5 42
RA2708 IKK16 2.0
uM
 2
IL18
 19.0 62
RA2159 Tofacitinib 0.3
uM
 2
IL18
 21.0 53
RA2159 2
IL18
 22.0 48
N2645 Tofacitinib 0.3
uM
 2
IL18
 23.0 57
N2645 2
IL18
 20.0 49
RA2708 Tofacitinib 0.3
uM
 2
IL18
 17.0 34
RA2708 2
IL18
 19.0 38
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL18
 19.5 68
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL18
 23.0 53
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL18
 17.0 44
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL18
 17.0 54
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL18
 17.0 51
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL18
 19.5 48
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL18
 21.0 37
RA2159 TNF-a 100
ng/mL
 2
IL18
 19.0 47
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL18
 17.0 45
N2645 TNF-a 100
ng/mL
 2
IL18
 20.0 62
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL18
 19.0 36
RA2708 TNF-a 100
ng/mL
 2
IL18
 20.0 27
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL18
 35.0 60