Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 33.0 63
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 35.0 79
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 29.5 64
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 31.0 59
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 27.0 71
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 36.0 65
RA2159 Poly(I:C) 2
ug/mL
 4
IL18
 34.0 71
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 29.0 61
N2645 Poly(I:C) 2
ug/mL
 4
IL18
 33.0 69
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 30.5 50
RA2708 Poly(I:C) 2
ug/mL
 4
IL18
 29.5 54
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 53.5 66
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 56.0 72
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 42.0 66
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 43.5 56
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 59.0 67
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 49.0 60
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 62.0 55
RA2159 IL-1 alpha 100
ng/mL
 4
IL18
 55.0 51
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 47.0 46
N2645 IL-1 alpha 100
ng/mL
 4
IL18
 42.0 61
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 59.0 39
RA2708 IL-1 alpha 100
ng/mL
 4
IL18
 60.0 40
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL18
 32.5 74
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL18
 33.0 63