Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 TNF-a 100
ng/mL
 1
IL18
 22.0 38
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 41.0 45
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 42.5 52
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 39.0 59
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 42.0 71
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 35.0 63
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 39.5 64
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 45.0 47
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 42.0 55
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 39.0 47
RA1869 IL-1 alpha 100
ng/mL
 1
IL18
 43.0 50
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 38.0 59
N2759 IL-1 alpha 100
ng/mL
 1
IL18
 38.0 41
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 48.0 39
RA1931 IL-1 alpha 100
ng/mL
 1
IL18
 45.5 70
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 43.0 39
N2586 IL-1 alpha 100
ng/mL
 1
IL18
 38.0 44
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 26.5 34
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 27.0 47
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 20.0 52
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 16.0 51
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 22.0 58
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 23.0 55
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 16.5 50
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 16.0 65