Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 5z-7-oxozeaenol 0.6
uM
1
IL18
15.5 40
N2586 IKK16 2.0
uM
1
IL18
22.0 46
RA1869 Tofacitinib 0.3
uM
1
IL18
20.0 61
RA1869 1
IL18
18.0 49
N2759 Tofacitinib 0.3
uM
1
IL18
24.0 61
N2759 1
IL18
18.0 52
RA1931 Tofacitinib 0.3
uM
1
IL18
20.0 58
RA1931 1
IL18
24.0 64
N2586 Tofacitinib 0.3
uM
1
IL18
16.5 30
N2586 1
IL18
21.5 56
RA1869 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
IL18
21.5 52
RA1869 IKK16 2.0
uM
TNF-a 100
ng/mL
1
IL18
23.0 57
N2759 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
IL18
19.5 66
N2759 IKK16 2.0
uM
TNF-a 100
ng/mL
1
IL18
24.0 83
RA1931 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
IL18
22.5 62
RA1931 IKK16 2.0
uM
TNF-a 100
ng/mL
1
IL18
25.0 55
N2586 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
IL18
19.0 52
N2586 IKK16 2.0
uM
TNF-a 100
ng/mL
1
IL18
21.0 57
RA1869 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
IL18
24.0 47
RA1869 TNF-a 100
ng/mL
1
IL18
20.5 62
N2759 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
IL18
21.0 53
N2759 TNF-a 100
ng/mL
1
IL18
21.0 64
RA1931 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
IL18
21.0 61
RA1931 TNF-a 100
ng/mL
1
IL18
26.5 58
N2586 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
IL18
21.0 30