Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 18.5 46
RA1869 Poly(I:C) 2
ug/mL
 1
IL18
 20.5 38
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 16.0 51
N2759 Poly(I:C) 2
ug/mL
 1
IL18
 21.0 53
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 24.0 51
RA1931 Poly(I:C) 2
ug/mL
 1
IL18
 22.0 45
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 22.0 39
N2586 Poly(I:C) 2
ug/mL
 1
IL18
 21.0 37
RA1869 5z-7-oxozeaenol 0.6
uM
 1
IL18
 30.0 47
RA1869 IKK16 2.0
uM
 1
IL18
 27.0 58
N2759 5z-7-oxozeaenol 0.6
uM
 1
IL18
 18.0 53
N2759 IKK16 2.0
uM
 1
IL18
 19.0 59
RA1931 5z-7-oxozeaenol 0.6
uM
 1
IL18
 28.0 41
RA1931 IKK16 2.0
uM
 1
IL18
 26.0 65
N2586 5z-7-oxozeaenol 0.6
uM
 1
IL18
 21.5 68
N2586 IKK16 2.0
uM
 1
IL18
 20.0 37
RA1869 Tofacitinib 0.3
uM
 1
IL18
 26.0 51
RA1869 1
IL18
 23.0 51
N2759 Tofacitinib 0.3
uM
 1
IL18
 20.0 52
N2759 1
IL18
 18.0 59
RA1931 Tofacitinib 0.3
uM
 1
IL18
 28.0 45
RA1931 1
IL18
 29.0 45
N2586 Tofacitinib 0.3
uM
 1
IL18
 21.5 46
N2586 1
IL18
 23.0 49
0
IL18
 17.0 61