Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1931 | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 124.5 | 50 | ||||
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 116.0 | 45 | |
| N2586 | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 91.5 | 72 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | 3 | IL12(p40) | 109.0 | 48 | ||||
| RA1869 | IKK16 | 2.0 | uM | 3 | IL12(p40) | 115.0 | 68 | ||||
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | 3 | IL12(p40) | 149.0 | 56 | ||||
| N2759 | IKK16 | 2.0 | uM | 3 | IL12(p40) | 116.0 | 74 | ||||
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | 3 | IL12(p40) | 124.5 | 64 | ||||
| RA1931 | IKK16 | 2.0 | uM | 3 | IL12(p40) | 118.0 | 57 | ||||
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | 3 | IL12(p40) | 121.0 | 64 | ||||
| N2586 | IKK16 | 2.0 | uM | 3 | IL12(p40) | 104.0 | 38 | ||||
| RA1869 | Tofacitinib | 0.3 | uM | 3 | IL12(p40) | 116.0 | 60 | ||||
| RA1869 | 3 | IL12(p40) | 142.0 | 46 | |||||||
| N2759 | Tofacitinib | 0.3 | uM | 3 | IL12(p40) | 110.0 | 70 | ||||
| N2759 | 3 | IL12(p40) | 130.0 | 47 | |||||||
| RA1931 | Tofacitinib | 0.3 | uM | 3 | IL12(p40) | 123.0 | 55 | ||||
| RA1931 | 3 | IL12(p40) | 115.5 | 48 | |||||||
| N2586 | Tofacitinib | 0.3 | uM | 3 | IL12(p40) | 107.0 | 47 | ||||
| N2586 | 3 | IL12(p40) | 89.0 | 67 | |||||||
| RA1869 | 3 | IL12(p40) | 89.5 | 46 | |||||||
| N2759 | 3 | IL12(p40) | 114.0 | 53 | |||||||
| RA1931 | 3 | IL12(p40) | 108.5 | 58 | |||||||
| N2586 | 3 | IL12(p40) | 83.0 | 59 | |||||||
| RA1869 | JNK-IN-8 | 3.0 | uM | 3 | IL12(p40) | 109.0 | 60 | ||||
| RA1869 | PH-797804 | 0.6 | uM | 3 | IL12(p40) | 144.5 | 34 |