Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 146.0 | 75 | |
| RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 136.0 | 55 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 156.0 | 67 | |
| N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 115.0 | 57 | |
| RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 145.0 | 62 | |
| RA1869 | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 134.0 | 59 | ||||
| N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 145.5 | 66 | |
| N2759 | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 129.0 | 58 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 162.0 | 52 | |
| RA1931 | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 138.0 | 49 | ||||
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 141.0 | 57 | |
| N2586 | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 114.0 | 44 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 105.0 | 49 | |
| RA1869 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 130.0 | 61 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 143.0 | 49 | |
| N2759 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 142.0 | 41 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 113.0 | 61 | |
| RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 124.0 | 44 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 119.0 | 63 | |
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 103.0 | 50 | |
| RA1869 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 105.0 | 55 | |
| RA1869 | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 114.0 | 56 | ||||
| N2759 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 125.0 | 60 | |
| N2759 | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 142.5 | 50 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 131.0 | 61 |