Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
N2759 | 3 | IL12(p40) | 117.5 | 62 | |||||||
RA1931 | Tofacitinib | 0.3 | uM | 3 | IL12(p40) | 123.0 | 57 | ||||
RA1931 | 3 | IL12(p40) | 110.0 | 47 | |||||||
N2586 | Tofacitinib | 0.3 | uM | 3 | IL12(p40) | 91.5 | 66 | ||||
N2586 | 3 | IL12(p40) | 90.0 | 63 | |||||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 94.5 | 64 | |
RA1869 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 92.0 | 53 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 109.0 | 79 | |
N2759 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 107.0 | 47 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 103.0 | 49 | |
RA1931 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 85.5 | 58 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 77.0 | 64 | |
N2586 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 80.0 | 51 | |
RA1869 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 112.5 | 36 | |
RA1869 | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 109.0 | 43 | ||||
N2759 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 130.0 | 47 | |
N2759 | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 125.5 | 52 | ||||
RA1931 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 104.0 | 44 | |
RA1931 | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 108.0 | 54 | ||||
N2586 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 84.0 | 63 | |
N2586 | Poly(I:C) | 2 | ug/mL | 3 | IL12(p40) | 88.0 | 47 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 135.0 | 49 | |
RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 124.0 | 68 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 162.0 | 71 | |
N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 146.5 | 70 |