Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-17
 72.0 52
RA1869 1
IL-17
 37.0 65
N2759 1
IL-17
 40.0 65
RA1931 1
IL-17
 42.0 69
N2586 1
IL-17
 38.0 58
RA1869 JNK-IN-8 3.0
uM
 1
IL-17
 43.0 63
RA1869 PH-797804 0.6
uM
 1
IL-17
 43.0 67
N2759 JNK-IN-8 3.0
uM
 1
IL-17
 41.5 62
N2759 PH-797804 0.6
uM
 1
IL-17
 37.0 57
RA1931 JNK-IN-8 3.0
uM
 1
IL-17
 45.0 69
RA1931 PH-797804 0.6
uM
 1
IL-17
 41.0 49
N2586 JNK-IN-8 3.0
uM
 1
IL-17
 39.5 54
N2586 PH-797804 0.6
uM
 1
IL-17
 44.0 59
RA1869 5z-7-oxozeaenol 0.6
uM
 1
IL-17
 39.5 60
RA1869 IKK16 2.0
uM
 1
IL-17
 40.0 61
N2759 5z-7-oxozeaenol 0.6
uM
 1
IL-17
 45.0 79
N2759 IKK16 2.0
uM
 1
IL-17
 35.0 56
RA1931 5z-7-oxozeaenol 0.6
uM
 1
IL-17
 41.0 68
RA1931 IKK16 2.0
uM
 1
IL-17
 40.0 58
N2586 5z-7-oxozeaenol 0.6
uM
 1
IL-17
 33.0 75
N2586 IKK16 2.0
uM
 1
IL-17
 38.0 55
RA1869 Tofacitinib 0.3
uM
 1
IL-17
 36.0 63
RA1869 1
IL-17
 37.0 59
N2759 Tofacitinib 0.3
uM
 1
IL-17
 40.0 65
N2759 1
IL-17
 40.0 54