Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 1
IL-17
 120.5 38
N2586 PH-797804 0.6
uM
 TNF-a 100
ng/mL
 1
IL-17
 105.5 50
RA1869 IL-1 alpha 100
ng/mL
 1
IL-17
 106.5 56
N2759 IL-1 alpha 100
ng/mL
 1
IL-17
 76.5 60
RA1931 IL-1 alpha 100
ng/mL
 1
IL-17
 84.0 61
N2586 IL-1 alpha 100
ng/mL
 1
IL-17
 109.5 66
RA1869 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-17
 83.0 47
RA1869 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-17
 75.0 51
N2759 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-17
 96.5 48
N2759 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-17
 80.5 58
RA1931 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-17
 100.0 67
RA1931 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-17
 79.0 69
N2586 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-17
 101.0 36
N2586 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-17
 79.0 69
RA1869 Poly(I:C) 2
ug/mL
 1
IL-17
 44.0 65
N2759 Poly(I:C) 2
ug/mL
 1
IL-17
 82.0 47
RA1931 Poly(I:C) 2
ug/mL
 1
IL-17
 70.5 52
N2586 Poly(I:C) 2
ug/mL
 1
IL-17
 93.5 68
RA1869 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-17
 39.0 67
RA1869 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-17
 60.0 59
N2759 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-17
 49.0 47
N2759 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-17
 73.0 53
RA1931 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-17
 59.0 57
RA1931 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-17
 70.5 66
N2586 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-17
 81.0 45