Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1869 | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 143.0 | 57 | ||||
| N2759 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 71.0 | 57 | |
| N2759 | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 91.0 | 49 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 161.0 | 55 | |
| RA1931 | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 153.0 | 53 | ||||
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 105.0 | 60 | |
| N2586 | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 87.0 | 67 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 59.0 | 61 | |
| RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 89.0 | 53 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 45.5 | 56 | |
| N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 60.0 | 53 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 73.0 | 62 | |
| RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 95.0 | 63 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 66.0 | 41 | |
| N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 65.0 | 45 | |
| RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 111.5 | 54 | |
| RA1869 | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 148.0 | 50 | ||||
| N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 82.0 | 55 | |
| N2759 | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 104.0 | 51 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 162.5 | 54 | |
| RA1931 | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 134.0 | 49 | ||||
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 118.5 | 34 | |
| N2586 | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 111.0 | 43 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 60.0 | 39 | |
| RA1869 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 75.0 | 35 |