Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-12 (p70) | 60.0 | 47 | ||||
| RA1869 | IKK16 | 2.0 | uM | 1 | IL-12 (p70) | 70.0 | 57 | ||||
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-12 (p70) | 62.0 | 71 | ||||
| N2759 | IKK16 | 2.0 | uM | 1 | IL-12 (p70) | 55.0 | 71 | ||||
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-12 (p70) | 90.0 | 65 | ||||
| RA1931 | IKK16 | 2.0 | uM | 1 | IL-12 (p70) | 91.0 | 67 | ||||
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-12 (p70) | 52.0 | 62 | ||||
| N2586 | IKK16 | 2.0 | uM | 1 | IL-12 (p70) | 68.0 | 51 | ||||
| RA1869 | Tofacitinib | 0.3 | uM | 1 | IL-12 (p70) | 91.5 | 66 | ||||
| RA1869 | 1 | IL-12 (p70) | 96.0 | 56 | |||||||
| N2759 | Tofacitinib | 0.3 | uM | 1 | IL-12 (p70) | 58.0 | 60 | ||||
| N2759 | 1 | IL-12 (p70) | 77.0 | 47 | |||||||
| RA1931 | Tofacitinib | 0.3 | uM | 1 | IL-12 (p70) | 105.5 | 48 | ||||
| RA1931 | 1 | IL-12 (p70) | 99.0 | 73 | |||||||
| N2586 | Tofacitinib | 0.3 | uM | 1 | IL-12 (p70) | 83.5 | 68 | ||||
| N2586 | 1 | IL-12 (p70) | 68.5 | 46 | |||||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 50.0 | 46 | |
| RA1869 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 95.0 | 54 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 67.5 | 56 | |
| N2759 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 81.0 | 65 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 97.5 | 62 | |
| RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 98.0 | 45 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 76.0 | 66 | |
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 83.0 | 55 | |
| RA1869 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 104.0 | 55 |