Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MIG
 54.0 59
RA2159 IL-1 alpha 100
ng/mL
 4
MIG
 47.0 45
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MIG
 81.0 60
N2645 IL-1 alpha 100
ng/mL
 4
MIG
 64.0 71
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MIG
 78.0 71
RA2708 IL-1 alpha 100
ng/mL
 4
MIG
 69.0 53
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MIG
 30.0 62
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
MIG
 46.0 67
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MIG
 40.0 78
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
MIG
 47.0 76
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MIG
 37.5 88
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
MIG
 100.0 60
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
MIG
 70.5 62
RA2159 TNF-a 100
ng/mL
 4
MIG
 65.0 74
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
MIG
 65.0 63
N2645 TNF-a 100
ng/mL
 4
MIG
 60.0 75
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
MIG
 166.5 56
RA2708 TNF-a 100
ng/mL
 4
MIG
 142.0 45
RA2159 5z-7-oxozeaenol 0.6
uM
 4
MIG
 29.0 42
RA2159 IKK16 2.0
uM
 4
MIG
 19.0 59
N2645 5z-7-oxozeaenol 0.6
uM
 4
MIG
 17.0 68
N2645 IKK16 2.0
uM
 4
MIG
 19.0 73
RA2708 5z-7-oxozeaenol 0.6
uM
 4
MIG
 26.0 70
RA2708 IKK16 2.0
uM
 4
MIG
 30.0 65
RA2159 Tofacitinib 0.3
uM
 4
MIG
 24.0 53