Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-6
 7071.0 72
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-6
 9896.0 75
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-6
 4172.0 79
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-6
 10713.5 100
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 21521.5 64
RA1869 TNF-a 100
ng/mL
 3
IL-6
 23649.0 74
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 6400.5 70
N2759 TNF-a 100
ng/mL
 3
IL-6
 7580.0 81
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 16501.0 64
RA1931 TNF-a 100
ng/mL
 3
IL-6
 19451.0 79
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 13523.0 73
N2586 TNF-a 100
ng/mL
 3
IL-6
 17688.5 78
RA1869 5z-7-oxozeaenol 0.6
uM
 3
IL-6
 1730.5 62
RA1869 IKK16 2.0
uM
 3
IL-6
 2908.0 77
N2759 5z-7-oxozeaenol 0.6
uM
 3
IL-6
 904.0 81
N2759 IKK16 2.0
uM
 3
IL-6
 767.0 76
RA1931 5z-7-oxozeaenol 0.6
uM
 3
IL-6
 2250.0 88
RA1931 IKK16 2.0
uM
 3
IL-6
 2793.5 78
N2586 5z-7-oxozeaenol 0.6
uM
 3
IL-6
 3236.0 79
N2586 IKK16 2.0
uM
 3
IL-6
 4770.0 77
RA1869 Tofacitinib 0.3
uM
 3
IL-6
 2853.0 64
RA1869 3
IL-6
 4845.0 70
N2759 Tofacitinib 0.3
uM
 3
IL-6
 653.0 81
N2759 3
IL-6
 891.0 76
RA1931 Tofacitinib 0.3
uM
 3
IL-6
 3177.0 71