Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 Poly(I:C) 2
ug/mL
 3
IL-6
 18200.0 69
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-6
 21044.0 75
RA1931 Poly(I:C) 2
ug/mL
 3
IL-6
 26970.0 54
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-6
 27004.0 73
N2586 Poly(I:C) 2
ug/mL
 3
IL-6
 27436.5 54
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 1681.0 69
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 14147.0 70
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 995.0 81
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 6836.0 83
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 3439.0 85
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 12578.0 80
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 3526.0 95
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 10319.0 65
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 32282.5 80
RA1869 IL-1 alpha 100
ng/mL
 3
IL-6
 33477.0 76
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 31418.0 68
N2759 IL-1 alpha 100
ng/mL
 3
IL-6
 32828.0 87
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 32282.0 61
RA1931 IL-1 alpha 100
ng/mL
 3
IL-6
 34375.0 71
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 34171.0 75
N2586 IL-1 alpha 100
ng/mL
 3
IL-6
 33716.0 73
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-6
 8888.5 66
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-6
 15435.5 72
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-6
 1005.0 50
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-6
 2591.0 79