Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 Poly(I:C) 2
ug/mL
 1
TNF-a
 81.0 43
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 53.5 72
RA1931 Poly(I:C) 2
ug/mL
 1
TNF-a
 69.5 66
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 65.0 69
N2586 Poly(I:C) 2
ug/mL
 1
TNF-a
 72.5 48
RA1869 5z-7-oxozeaenol 0.6
uM
 1
TNF-a
 22.5 76
RA1869 IKK16 2.0
uM
 1
TNF-a
 18.0 63
N2759 5z-7-oxozeaenol 0.6
uM
 1
TNF-a
 22.0 60
N2759 IKK16 2.0
uM
 1
TNF-a
 19.0 58
RA1931 5z-7-oxozeaenol 0.6
uM
 1
TNF-a
 20.0 72
RA1931 IKK16 2.0
uM
 1
TNF-a
 22.0 59
N2586 5z-7-oxozeaenol 0.6
uM
 1
TNF-a
 25.0 59
N2586 IKK16 2.0
uM
 1
TNF-a
 22.0 47
RA1869 Tofacitinib 0.3
uM
 1
TNF-a
 21.0 65
RA1869 1
TNF-a
 20.0 77
N2759 Tofacitinib 0.3
uM
 1
TNF-a
 22.0 60
N2759 1
TNF-a
 21.0 57
RA1931 Tofacitinib 0.3
uM
 1
TNF-a
 22.0 72
RA1931 1
TNF-a
 22.0 61
N2586 Tofacitinib 0.3
uM
 1
TNF-a
 25.0 49
N2586 1
TNF-a
 24.5 52
0
TNF-a
 20.0 57
0
TNF-a
 18.0 55
0
TNF-a
 20.0 52
0
TNF-a
 22.0 68