Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-1B
 383.0 77
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-1B
 337.0 81
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-1B
 396.5 96
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-1B
 398.0 76
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1B
 459.0 63
RA1869 TNF-a 100
ng/mL
 1
IL-1B
 427.0 62
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1B
 363.0 90
N2759 TNF-a 100
ng/mL
 1
IL-1B
 440.0 59
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1B
 471.5 76
RA1931 TNF-a 100
ng/mL
 1
IL-1B
 512.5 72
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1B
 427.0 71
N2586 TNF-a 100
ng/mL
 1
IL-1B
 414.0 61
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 15.0 57
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 21.0 77
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 13.5 60
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 21.5 66
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 16.0 78
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 28.0 71
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 19.0 65
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 24.5 52
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 90.0 67
RA1869 IL-1 alpha 100
ng/mL
 1
IL-1B
 83.0 70
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 81.0 65
N2759 IL-1 alpha 100
ng/mL
 1
IL-1B
 93.5 72
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 81.5 68