Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 PH-797804 0.6
uM
 1
IL-1B
 15.5 68
RA1931 JNK-IN-8 3.0
uM
 1
IL-1B
 21.0 59
RA1931 PH-797804 0.6
uM
 1
IL-1B
 15.0 72
N2586 JNK-IN-8 3.0
uM
 1
IL-1B
 19.0 92
N2586 PH-797804 0.6
uM
 1
IL-1B
 17.0 79
RA1869 5z-7-oxozeaenol 0.6
uM
 1
IL-1B
 20.0 65
RA1869 IKK16 2.0
uM
 1
IL-1B
 15.0 97
N2759 5z-7-oxozeaenol 0.6
uM
 1
IL-1B
 16.5 68
N2759 IKK16 2.0
uM
 1
IL-1B
 12.0 81
RA1931 5z-7-oxozeaenol 0.6
uM
 1
IL-1B
 14.0 75
RA1931 IKK16 2.0
uM
 1
IL-1B
 16.0 88
N2586 5z-7-oxozeaenol 0.6
uM
 1
IL-1B
 13.0 95
N2586 IKK16 2.0
uM
 1
IL-1B
 16.5 62
RA1869 Tofacitinib 0.3
uM
 1
IL-1B
 14.0 71
RA1869 1
IL-1B
 14.0 90
N2759 Tofacitinib 0.3
uM
 1
IL-1B
 16.0 93
N2759 1
IL-1B
 13.5 64
RA1931 Tofacitinib 0.3
uM
 1
IL-1B
 18.0 57
RA1931 1
IL-1B
 18.5 76
N2586 Tofacitinib 0.3
uM
 1
IL-1B
 18.0 84
N2586 1
IL-1B
 17.0 63
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-1B
 353.0 63
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-1B
 406.5 70
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-1B
 392.0 88
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-1B
 393.0 78