Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 IL-1 alpha 100
ng/mL
 1
IL-1B
 87.0 59
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 98.0 73
N2586 IL-1 alpha 100
ng/mL
 1
IL-1B
 83.0 69
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 15.0 58
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 23.0 68
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 18.0 73
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 16.0 47
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 15.0 65
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 20.0 61
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 15.0 64
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 16.0 69
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 38.0 67
RA1869 Poly(I:C) 2
ug/mL
 1
IL-1B
 63.0 36
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 54.5 82
N2759 Poly(I:C) 2
ug/mL
 1
IL-1B
 69.0 71
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 50.0 87
RA1931 Poly(I:C) 2
ug/mL
 1
IL-1B
 66.0 61
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 58.0 75
N2586 Poly(I:C) 2
ug/mL
 1
IL-1B
 68.0 62
RA1869 5z-7-oxozeaenol 0.6
uM
 1
IL-1B
 13.0 88
RA1869 IKK16 2.0
uM
 1
IL-1B
 16.0 53
N2759 5z-7-oxozeaenol 0.6
uM
 1
IL-1B
 16.0 67
N2759 IKK16 2.0
uM
 1
IL-1B
 14.0 64
RA1931 5z-7-oxozeaenol 0.6
uM
 1
IL-1B
 13.0 85
RA1931 IKK16 2.0
uM
 1
IL-1B
 13.0 61