Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 TNF-a 100
ng/mL
 4
MMP-1
 144.5 70
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
MMP-1
 27687.0 55
RA2708 TNF-a 100
ng/mL
 4
MMP-1
 38971.0 43
RA2159 5z-7-oxozeaenol 0.6
uM
 4
MMP-1
 223.0 49
RA2159 IKK16 2.0
uM
 4
MMP-1
 253.0 62
N2645 5z-7-oxozeaenol 0.6
uM
 4
MMP-1
 75.0 63
N2645 IKK16 2.0
uM
 4
MMP-1
 74.0 41
RA2708 5z-7-oxozeaenol 0.6
uM
 4
MMP-1
 705.5 54
RA2708 IKK16 2.0
uM
 4
MMP-1
 851.0 57
RA2159 Tofacitinib 0.3
uM
 4
MMP-1
 169.0 71
RA2159 4
MMP-1
 184.5 58
N2645 Tofacitinib 0.3
uM
 4
MMP-1
 58.0 64
N2645 4
MMP-1
 64.0 55
RA2708 Tofacitinib 0.3
uM
 4
MMP-1
 1156.0 62
RA2708 4
MMP-1
 1701.0 64
RA2159 4
MMP-1
 305.0 37
N2645 4
MMP-1
 71.0 45
RA2708 4
MMP-1
 946.0 57
RA2159 JNK-IN-8 3.0
uM
 4
MMP-1
 227.0 49
RA2159 PH-797804 0.6
uM
 4
MMP-1
 280.0 59
N2645 JNK-IN-8 3.0
uM
 4
MMP-1
 105.5 64
N2645 PH-797804 0.6
uM
 4
MMP-1
 88.0 57
RA2708 JNK-IN-8 3.0
uM
 4
MMP-1
 1448.5 50
RA2708 PH-797804 0.6
uM
 4
MMP-1
 1470.0 51
RA2159 Poly(I:C) 2
ug/mL
 4
MMP-1
 464.5 44