Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 2
MMP-1
 189.0 52
N2645 Tofacitinib 0.3
uM
 2
MMP-1
 112.5 56
N2645 2
MMP-1
 98.0 52
RA2708 Tofacitinib 0.3
uM
 2
MMP-1
 1145.0 61
RA2708 2
MMP-1
 1262.0 51
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-1
 246.5 46
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-1
 1998.5 56
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-1
 98.0 47
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-1
 105.0 63
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-1
 1063.0 56
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-1
 14853.0 67
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-1
 1605.5 66
RA2159 TNF-a 100
ng/mL
 2
MMP-1
 3021.5 48
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-1
 189.0 75
N2645 TNF-a 100
ng/mL
 2
MMP-1
 82.0 55
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-1
 22465.5 48
RA2708 TNF-a 100
ng/mL
 2
MMP-1
 32442.0 57
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-1
 239.0 30
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-1
 398.0 65
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-1
 150.0 64
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-1
 168.0 63
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-1
 794.5 56
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-1
 13902.0 67
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MMP-1
 4245.0 53
RA2159 IL-1 alpha 100
ng/mL
 2
MMP-1
 3205.0 67