Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 PH-797804 0.6
uM
3
IL-5
11.0 52
RA1931 JNK-IN-8 3.0
uM
3
IL-5
9.0 64
RA1931 PH-797804 0.6
uM
3
IL-5
10.5 62
N2586 JNK-IN-8 3.0
uM
3
IL-5
7.0 49
N2586 PH-797804 0.6
uM
3
IL-5
8.5 36
0
IL-5
12.0 19
0
IL-5
11.0 21
0
IL-5
6.0 15
RA2159 5z-7-oxozeaenol 0.6
uM
4
IL-5
10.0 28
RA2159 IKK16 2.0
uM
4
IL-5
10.0 43
N2645 5z-7-oxozeaenol 0.6
uM
4
IL-5
8.0 34
N2645 IKK16 2.0
uM
4
IL-5
11.0 38
RA2708 5z-7-oxozeaenol 0.6
uM
4
IL-5
10.0 53
RA2708 IKK16 2.0
uM
4
IL-5
12.5 38
RA2159 Tofacitinib 0.3
uM
4
IL-5
12.5 40
RA2159 4
IL-5
10.0 33
N2645 Tofacitinib 0.3
uM
4
IL-5
9.0 36
N2645 4
IL-5
8.0 27
RA2708 Tofacitinib 0.3
uM
4
IL-5
9.0 22
RA2708 4
IL-5
13.0 29
RA2159 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
4
IL-5
9.0 39
RA2159 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
4
IL-5
11.0 40
N2645 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
4
IL-5
10.5 38
N2645 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
4
IL-5
9.0 37
RA2708 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
4
IL-5
9.5 26