Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-1B
 279.0 60
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-1B
 307.0 68
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-1B
 337.0 71
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-1B
 274.0 68
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-1B
 362.5 70
RA2159 TNF-a 100
ng/mL
 2
IL-1B
 362.0 69
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-1B
 263.0 74
N2645 TNF-a 100
ng/mL
 2
IL-1B
 336.0 75
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-1B
 310.0 59
RA2708 TNF-a 100
ng/mL
 2
IL-1B
 349.0 47
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 16.0 53
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 20.5 68
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 15.0 91
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 16.0 75
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 18.0 47
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 25.0 66
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 75.0 69
RA2159 IL-1 alpha 100
ng/mL
 2
IL-1B
 68.0 68
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 30.5 66
N2645 IL-1 alpha 100
ng/mL
 2
IL-1B
 33.0 53
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-1B
 73.0 57
RA2708 IL-1 alpha 100
ng/mL
 2
IL-1B
 68.5 64
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-1B
 15.0 74
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-1B
 23.0 65
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-1B
 15.0 85