Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
IL-16
 19.5 50
N2586 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
IL-16
 19.0 55
N2586 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
IL-16
 18.0 49
N2586 Ruxolitinib 0.3
uM
 2
IL-16
 21.5 60
RA2159 IL-17A 100
ng/mL
 2
IL-16
 19.0 63
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
IL-16
 19.0 73
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
IL-16
 19.0 62
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
IL-16
 18.0 50
RA2159 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
IL-16
 20.0 62
RA2159 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
IL-16
 19.0 36
RA2159 Tofacitinib 0.3
uM
 2
IL-16
 21.0 37
N2586 IL-17A 100
ng/mL
 2
IL-16
 17.5 46
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
IL-16
 17.0 71
N2586 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
IL-16
 15.0 19
N2586 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
IL-16
 17.0 17
N2586 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
IL-16
 19.5 46
N2586 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
IL-16
 23.0 57
N2586 Tofacitinib 0.3
uM
 2
IL-16
 20.5 74
RA2159 2
IL-16
 18.0 82
RA2159 EO1428 1.0
uM
 2
IL-16
 19.0 53
RA2159 PI103 0.1
uM
 2
IL-16
 18.0 60
RA2159 Sigma A6730 3.0
uM
 2
IL-16
 18.0 46
RA2159 JNK-IN-8 3.0
uM
 2
IL-16
 20.0 62
RA2159 JNK-IN-11 0.3
uM
 2
IL-16
 17.5 74
RA2159 IKK16 2.0
uM
 2
IL-16
 20.0 64