Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Ruxolitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
MCP3
 77.0 38
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
MCP3
 88.0 49
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
MCP3
 83.5 36
0
MCP3
 20.0 67
RA2159 2
MCP3
 26.0 64
RA2159 EO1428 1.0
uM
 2
MCP3
 28.0 54
RA2159 PI103 0.1
uM
 2
MCP3
 27.5 66
RA2159 Sigma A6730 3.0
uM
 2
MCP3
 32.0 83
RA2159 JNK-IN-8 3.0
uM
 2
MCP3
 26.0 68
RA2159 JNK-IN-11 0.3
uM
 2
MCP3
 32.0 56
RA2159 2
MCP3
 32.0 59
N2586 2
MCP3
 56.0 74
N2586 EO1428 1.0
uM
 2
MCP3
 59.0 59
N2586 PI103 0.1
uM
 2
MCP3
 55.0 66
N2586 Sigma A6730 3.0
uM
 2
MCP3
 69.0 55
N2586 JNK-IN-8 3.0
uM
 2
MCP3
 49.0 55
N2586 JNK-IN-11 0.3
uM
 2
MCP3
 57.0 39
N2586 2
MCP3
 71.0 65
0
MCP3
 19.0 63
0
MCP3
 20.0 64
RA2159 TNF-a 100
ng/mL
 2
MCP3
 102.5 76
RA2159 EO1428 1.0
uM
 TNF-a 100
ng/mL
 2
MCP3
 76.0 60
RA2159 PI103 0.1
uM
 TNF-a 100
ng/mL
 2
MCP3
 81.0 61
RA2159 Sigma A6730 3.0
uM
 TNF-a 100
ng/mL
 2
MCP3
 76.5 64
RA2159 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 2
MCP3
 66.0 61